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Accutane supplement interactions.Isotretinoin
Isotretinoin is a vitamin A derivative that belongs to the class of medications called retinoids. Retinoids are typically used to treat skin problems. Isotretinoin is used to treat severe types of acne, such as nodular or inflammatory acne, where other medications with less potential for severe side effects have failed to help.
It may also be used to treat acne conglobata and recalcitrant acne. Isotretinoin helps to reduce sebum production, which is often associated with bacteria that contributes to acne. In many cases, it can produce remission of the acne condition. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor.
Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. Record your current acne treatment and concerns to help your doctor find the best management strategies.
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The usual starting daily dose is 0. Based on body weight, severity of acne, and your response to the medication, your doctor will then adjust your dose.
Isotretinoin should be taken as a single dose or in 2 divided doses during the day. Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. Your acne may get worse temporarily, before it gets better.
Your doctor will adjust your daily dose after the initial treatment depending on your response to the medication. Food increases the amount of medication available to the body. It also helps to reduce upset stomach. For these reasons, isotretinoin medication should be taken with food. The first signs of healing usually occur after 2 to 3 weeks of treatment, however, it may take 1 or 2 months before you see beneficial effects. The complete course of treatment usually lasts 12 to 16 weeks.
Most people with severe acne notice a marked improvement after 1 or 2 courses of treatment. You may continue to see even more improvement in your acne condition for several months after you have stopped taking the medication. If any of your side effects do not clear up in a few weeks after you stop taking your medication, speak to your doctor.
Be sure to read the patient information that comes with each package of medication. It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature, in the original package, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater e. Ask your pharmacist how to dispose of medications that are no longer needed or have expired. Isotretinoin should not be taken by women who may become pregnant unless all of the following conditions apply:. Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses.
Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication.
If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention. Stop taking the medication and seek immediate medical attention if any of the following occur:.
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Behaviour changes and suicidal thoughts: Some people taking this medication have experienced depression, including thoughts of suicide.
If you experience any behaviour change or symptoms such as sad mood, hopelessness, feelings of guilt, loss of pleasure or interest in activities, changes in sleep pattern, irritability, or restlessness while taking this medication, contact your doctor immediately.
If you are at risk for developing depression or have a history of depression, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Family members or caregivers of people who are taking this medication should contact the person's doctor immediately if they notice unusual behaviour changes. Birth control: Isotretinoin causes birth defects in a large percentage of babies born to women who take this medication during pregnancy.
Isotretinoin interacts with hormonal birth control i. Two reliable forms of birth control should be used at the same time during treatment unless abstinence is the chosen method. Birth control must be used for at least one month before starting isotretinoin, during treatment with this medication and for at least one month after stopping the isotretinoin. Blood donation: You should not give blood during treatment with isotretinoin and for one month after stopping treatment in case the blood is given to a pregnant woman.
Bones and joints: Isotretinoin may cause some minor bone changes. Talk to your doctor if you notice aches or pains in the bones or joints, or have difficulty moving. Your doctor may monitor you for bone changes while you are taking this medication.
Cholesterol: Isotretinoin can cause increases in cholesterol and other lipids in the blood. If you are already at an increased risk of developing high cholesterol, for example if you have a family history of high cholesterol, diabetes, are overweight, or have an increased alcohol intake, you are more likely to experience this. If you are at any increased risk of developing increased blood lipids, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Contact lenses: This medication may cause dry eyes. If you use contact lenses you may find them uncomfortable to wear. You can help manage dry eyes by using a lubricating eye ointment or replacement tears. Diabetes: Isotretinoin may cause a loss of control of blood sugar levels for people with diabetes.
If you have diabetes, or anyone in your family has diabetes, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
You may need to check your blood glucose levels more often. Inflammatory bowel disease: This medication may cause irritation in the digestive system. If you experience stomach pain, rectal bleeding or diarrhea, contact your doctor immediately. Liver disease: Several cases of hepatitis inflammation of the liver have been reported that are considered to be possibly or probably related to isotretinoin therapy. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Muscle effects: There have been reports of muscle damage associated with use of isotretinoin, especially after strenuous physical activity. Report any unexplained muscle pain, tenderness, weakness or cramps, or any brown or discoloured urine to your doctor immediately, particularly if you are also experiencing malaise a general feeling of being unwell or fever.
Neurologic: Isotretinoin has been linked to causing intracranial hypertension, also known as pseudotumor cerebri. Early symptoms of this condition include headache, nausea, vomiting, and visual disturbances.
If you have these symptoms call your doctor immediately. Night vision: Decreased night vision has been reported during isotretinoin therapy. Because some patients experience sudden onset of vision problems, use caution when driving or operating any vehicle at night. Report any vision changes to your doctor. Pancreatitis: Isotretinoin can cause the pancreas to become inflamed. If you have a history of pancreatitis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Report signs of pancreatitis such as abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, or swollen abdomen to your doctor immediately. If you have a history of pancreatitis, gallstones, alcoholism, or high triglycerides, you may be more at risk of experiencing this. Skin care: Isotretinoin causes irritated, dry skin and lips. Ask your doctor or pharmacist for appropriate moisturizers and lip balms to use to prevent severe dryness.
While you are taking isotretinoin, avoid exfoliators, waxing and dermabrasion, or laser procedures. Skin rash: Isotretinoin may cause skin rash or itchiness. Rarely, people taking isotretinoin experience a severe skin reaction that can be life threatening. If you experience a rash that gets worse, or develops into blisters, sores on the lips or eyes, or covers a large area of the body, contact your doctor immediately.
Sun sensitivity: Isotretinoin may make you more likely to burn in the sun. Use appropriate measures to prevent excessive exposure to the sun.
Accutane supplement interactions.Taking isotretinoin capsules with other medicines and herbal supplements
- Accutane supplement interactions
You may continue to see even more improvement in your acne condition for several months after you have stopped taking the medication. If any of your side effects do not clear up in a few weeks after you stop taking your medication, speak to your doctor. Be sure to read the patient information that comes with each package of medication. It is important that this medication be taken exactly as prescribed by your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature, in the original package, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater e. Ask your pharmacist how to dispose of medications that are no longer needed or have expired. Isotretinoin should not be taken by women who may become pregnant unless all of the following conditions apply:.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Stop taking the medication and seek immediate medical attention if any of the following occur:. Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication. Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health.
These factors may affect how you should use this medication. Behaviour changes and suicidal thoughts: Some people taking this medication have experienced depression, including thoughts of suicide.
If you experience any behaviour change or symptoms such as sad mood, hopelessness, feelings of guilt, loss of pleasure or interest in activities, changes in sleep pattern, irritability, or restlessness while taking this medication, contact your doctor immediately. If you are at risk for developing depression or have a history of depression, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Family members or caregivers of people who are taking this medication should contact the person's doctor immediately if they notice unusual behaviour changes. Birth control: Isotretinoin causes birth defects in a large percentage of babies born to women who take this medication during pregnancy. Isotretinoin interacts with hormonal birth control i. Two reliable forms of birth control should be used at the same time during treatment unless abstinence is the chosen method.
Birth control must be used for at least one month before starting isotretinoin, during treatment with this medication and for at least one month after stopping the isotretinoin. Blood donation: You should not give blood during treatment with isotretinoin and for one month after stopping treatment in case the blood is given to a pregnant woman. While you are taking isotretinoin and for at least 6 months after your last dose: Do not use wax hair removers or have dermabrasion or laser skin treatments.
Scarring may result. Isotretinoin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors.
Avoid driving or hazardous activity until you know how this medicine will affect you. Isotretinoin may impair your vision, especially at night. Use Isotretinoin Accutane exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Each prescription of isotretinoin must be filled within 7 days of the date it was written by your doctor.
You will receive no more than a day supply of isotretinoin at one time. Always take isotretinoin with a full glass of water. Do not chew or suck on the capsule. Swallow it whole. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Information expires December This information does not replace the advice of a doctor.
Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. Drug Information Isotretinoin is a modified vitamin A molecule used to treat severe acne vulgaris. Common brand names: Accutane, Amnesteem, Claravis, Sotret. Isotretinoin comes with a patient information form and Medication Guide.
It is very important that you read and understand this information. Be sure to carefully follow these instructions and ask your doctor if you have any questions. Be sure to ask your doctor if you have any questions about this program. It is very important that you understand and follow all of the requirements. You will not get another prescription unless you follow the instructions for the program. Swallow the capsule whole with a full glass 8 ounces of water or other liquid.
Do not crush, break, chew, or suck the capsule. It is very important that you take isotretinoin only as directed by your doctor.
Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. It is very important that you not share this medicine with anyone else because of the risk of birth defects and other serious side effects.
Different brands may not work the same way. If you refill your medicine and it looks different, check with your pharmacist. The dose of this medicine will be different for different patients.
Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Do not double doses. Do not take extra medicine to make up for a missed dose. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.
Isotretinoin causes birth defects in humans if taken during pregnancy. If you suspect that you may have become pregnant, check with your doctor right away. Using this medicine while you are pregnant can cause very serious birth defects. Use two forms of effective birth control to keep from getting pregnant 1 month before beginning treatment, while you are using this medicine even if the medicine is temporarily stopped , and for at least 1 month after you stop taking the medicine.
The most effective forms of birth control are hormone birth control pills, patches, shots, vaginal rings, or implants, an IUD, or a vasectomy for men. One of these forms of birth control should be combined with a condom, a diaphragm, or a cervical cap. Isotretinoin must not be taken by women of reproductive age who may become pregnant unless 2 effective forms of birth control have been used for at least 1 month before the start of treatment. Contraception must be continued during the period of treatment, which is up to 20 weeks, and for 1 month after isotretinoin is stopped.
Be sure that you have discussed this information with your doctor. If you are a woman who is able to have children, you must have 2 pregnancy tests before beginning treatment with isotretinoin to make sure you are not pregnant. The second pregnancy test must be taken at least 19 days after the first test and during the first 5 days of the menstrual period immediately before beginning treatment.
Isotretinoin is a modified vitamin A molecule used to treat severe acne vulgaris. Preliminary research has found that combined administration of isotretinoin and vitamin E alpha-tocopherol substantially reduces the initial toxicity of high-dose isotretinoin without reducing drug efficacy. Additional research is needed to further clarify this potentially beneficial interaction.
Although little is known about how isotretinoin interacts with real vitamin A, the two are structurally similar and have similar toxicities. Therefore, people taking isotretinoin should avoid vitamin A supplements at levels higher than typically found in a multivitamin 10, IU per day.
Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. The TraceGains knowledgebase does not contain every possible interaction.
Learn more about TraceGains, the company. The information presented by TraceGains is for informational purposes only. It is based on scientific studies human, animal, or in vitroclinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available.
Information expires December This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Drug Information Isotretinoin is a modified vitamin A molecule used to treat severe acne vulgaris. Common brand names: Accutane, Amnesteem, Claravis, Sotret. What Are Nutrient Interactions. Types of interactions: Beneficial Adverse Check. Replenish Depleted Nutrients none. Reduce Side Effects Vitamin E Preliminary research has found that combined administration of isotretinoin and vitamin E alpha-tocopherol substantially reduces the initial toxicity of high-dose isotretinoin without reducing drug efficacy.
Support Medicine none. Reduces Effectiveness none. Potential Negative Interaction Vitamin A Although little is known about how isotretinoin interacts with real vitamin A, the two are structurally similar and have similar toxicities. Explanation Required none. The Drug-Nutrient Interactions table may not include every possible interaction.
Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers' package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist. Top of the page Next Section:. Previous Section: Drug Information Top of the page.
All rights reserved. Search the Healthwise Knowledgebase. Help Healthwise Index. Topic Contents Drug Information. Isotretinoin Drug Information Isotretinoin is a modified vitamin A molecule used to treat severe acne vulgaris.
Support Medicine none Reduces Effectiveness none Potential Negative Interaction Vitamin A Although little is known about how isotretinoin interacts with real vitamin A, the two are structurally similar and have similar toxicities. Explanation Required none The Drug-Nutrient Interactions table may not include every possible interaction.
There are drugs known to interact with Accutane (isotretinoin), along with 5 disease interactions, and 3 alcohol/food interactions. Drug Interactions. Although certain medicines should not be used together at all, in other cases two different medicines may be used together. Vitamin supplements: You should not take vitamin supplements containing vitamin A if you also take isotretinoin as this may increase the side effects of vitamin. Isotretinoin is a form of vitamin A that is used to treat severe nodular acne that has not responded to other treatments. I do not recommend my patients take any supplements other than a regular multi-vitamin while on Accutane. Particularly, do not take a straight. Isotretinoin is used to treat severe, disfiguring nodular acne.Isotretinoin is a form of vitamin A that is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.
Isotretinoin may also be used for purposes not listed in this medication guide. Isotretinoin can cause miscarriage, premature birth, severe birth defects, or death of a baby if the mother takes this medicine at the time of conception or during pregnancy.
Even one dose of isotretinoin can cause major birth defects of the baby's ears, eyes, face, skull, heart, and brain. Never use isotretinoin if you are pregnant or able to become pregnant.
For Women: Unless you have had your uterus and ovaries removed total hysterectomy or have been in menopause for at least 12 months in a row, you are considered to be able to get pregnant.
You must have 2 negative pregnancy tests before you start taking isotretinoin, before each prescription is refilled, right after you take your last dose of isotretinoin, and again 30 days later.
You must agree in writing to use two specific forms of birth control beginning 30 days before you start taking isotretinoin and ending 30 days after your last dose.
Both a primary and a secondary form of birth control must be used together. Stop using isotretinoin and call your doctor at once if you have unprotected sex, if you quit using birth control, if your period is late, or if you think you might be pregnant. Not having sexual intercourse abstinence is the most effective method of preventing pregnancy. Get emergency medical help if you have signs of an allergic reaction hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Do not take a vitamin or mineral supplement that contains vitamin A, unless your doctor tells you to. Do not donate blood while taking isotretinoin and for at least 30 days after you stop taking it.
Donated blood that is later given to a pregnant woman could lead to birth defects in her baby if the blood contains any level of isotretinoin. While you are taking isotretinoin and for at least 6 months after your last dose: Do not use wax hair removers or have dermabrasion or laser skin treatments.
Scarring may result. Isotretinoin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors. Avoid driving or hazardous activity until you know how this medicine will affect you.
Isotretinoin may impair your vision, especially at night. Use Isotretinoin Accutane exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Use the medicine exactly as directed. Each prescription of isotretinoin must be filled within 7 days of the date it was written by your doctor. You will receive no more than a day supply of isotretinoin at one time. Always take isotretinoin with a full glass of water.
Do not chew or suck on the capsule. Swallow it whole. Use this medicine for the full prescribed length of time. Your acne may seem to get worse at first, but should then begin to improve. Never share this medicine with another person, even if they have the same symptoms you have. Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. Health Conditions A-Z. Health Tools. See All. DailyOM Courses. Isotretinoin Accutane. Reviewed: October 12, Primary forms of birth control include: tubal ligation tubes tied ; vasectomy of the male sexual partner; an IUD intrauterine device ; estrogen-containing birth control pills not mini-pills ; and hormonal birth control patches, implants, injections, or vaginal ring.
Secondary forms of birth control include: a male latex condom with or without spermicide; a diaphragm plus a spermicide; a cervical cap plus a spermicide; and a vaginal sponge containing a spermicide. You should not use isotretinoin if you are allergic to it. Tell your doctor if you have ever had: depression or mental illness; asthma; liver disease; diabetes; heart disease or high cholesterol; osteoporosis or low bone mineral density; an eating disorder such as anorexia; a food or drug allergy; or an intestinal disorder such as inflammatory bowel disease or ulcerative colitis.
Do not breastfeed. Not approved for use by anyone younger than 12 years old. Side Effects. Side Effects What are the side effects of Isotretinoin Accutane? Stop using isotretinoin and call your doctor at once if you have: problems with your vision or hearing; muscle or joint pain, bone pain, back pain; increased thirst, increased urination; hallucinations, see or hearing things that are not real ; symptoms of depression --unusual mood changes, crying spells, feelings of low self-worth, loss of interest in things you once enjoyed, new sleep problems, thoughts about hurting yourself; signs of liver or pancreas problems --loss of appetite, upper stomach pain that may spread to your back , nausea or vomiting, fast heart rate, dark urine, jaundice yellowing of the skin or eyes ; severe stomach problems --severe stomach or chest pain, pain when swallowing, heartburn, diarrhea, rectal bleeding, bloody or tarry stools; or increased pressure inside the skull --severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.
Common side effects may include: dryness of your skin, lips, eyes, or nose you may have nosebleeds ; vision problems; headache, back pain, joint pain, muscle problems; skin reactions; or cold symptoms such as stuffy nose, sneezing, sore throat. Based on FDA pregnancy categories. Interactions What drugs and food should I avoid while taking Isotretinoin Accutane?
Follow all directions about taking isotretinoin with or without food. Store at room temperature away from moisture, heat, and light. What should I do if I missed a dose of Isotretinoin Accutane? If you think you or someone else may have overdosed on: Isotretinoin Accutane , call your doctor or the Poison Control center. If someone collapses or isn't breathing after taking Isotretinoin Accutane , call See More.
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