Looking for: Vaccines for COVID – your questions answered Click here Covid-19 vaccine and prednisone Sailler 1 , A. Blancher 2 , F. Abravanel 3 , J. Izopet 4 , C. Bost 5 , E. Treiner 6 , N. Congy 7 , Y. Figure 1. There is little evidence regarding the effect of corticosteroid, a potent anti-inflammatory agent, on the immunogenicity of the COVID vaccine, which would be essential data to guide patients on corticosteroid use 8. During mass vaccination of healthcare workers HCWs with ChAd, several HCWs who used corticosteroid agents for various reasons experienced lower reactogenicity than those who did not. A prospective cohort study evaluating post-vaccination reactogenicity and immunogenicity was conducted in the Republic of Korea, at a bed tertiary care hospital which has more than 5, HCWs. The first doses of ChAd were administered between March and May , and the second dose occurred 10 to 12 weeks after the first dose. The first and second BNT vaccinations were administer